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Von Willebrand Disease

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Ladan Mohammad-Zadeh, DVM, DACVECC, gives a quick overview of Von Willebrand disease and discusses the treatment strategy for a dog previously diagnosed with the disease that presented to the hospital needing an exploratory laparotomy.

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Ladan Mohammad-Zadeh's picture
Ladan Mohammad-Zadeh


Enrolled: 08/2011

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Rita Medina-Deihl's picture

What is the name of the supernatant from the FFP that was given to the patient?

Ladan Mohammad-Zadeh's picture

HI! Thanks for you question - it's a great one. The product is actually called "cryo-poor plasma". Just as it sounds, it is fresh frozen plasma that does not have any cryoprecipitate in it, so it is deficient in Factors VIII and VWB. This cryo-poor plasma still has active Vitamin K dependent factors like II, VII, IX, and X along with plasma proteins like albumin. It is still useful to treat conditions like anticoagulant rodenticide toxicity or for colloid support. Fresh frozen and frozen plasma are usually so overstocked, however, that most blood banks do not keep or sell the cryo-poor products.